Drug Error-Renal Failure
What is Drug-Induced Renal Failure (DIRF)? [1],[2]
Drug-induced renal failure (DIRF) is a type of acute kidney injury (AKI). It occurs when the kidneys suddenly stop making urine, which is how each kidney controls and clears out excess fluids, salts and waste products from the blood stream. Another term used to describe acute kidney injury is acute renal failure (ARF).
If a drug-induced renal failure is not caught early, and treated, the damage can progress to chronic kidney disease (CKD), or worse-end stage renal disease (ESRD).
End stage renal disease typically requires regular dialysis or a kidney transplant for the patient to live.
What are the causes of drug-induced renal failure (DIRF)?
Drug induced-renal failure typically affects patients with risk factors, such as being admitted into the hospital, high blood pressure, or chronic conditions such as diabetes.
Patients either start on new medications, have the dose of their medications increased, or have new medications prescribed to them. There are doctors, pharmacists and nurses in hospitals and out-patient medical facilities to identify and prevent drug-induced renal failure.
What are symptoms of drug-induced renal failure?
Not all patients experience the following symptoms. Some patients in the beginning stages of drug-induced renal failure may not have obvious symptoms. Still, one should look for:
- Decreased urination or not urinating at all
- Red or brown urine (blood in urine)
- Swelling of the lower body (legs, ankles, feet)
- Nausea
- Vomiting
- Increased hunger
- Feeling more tired or weak than usual
- Feeling or acting confused
- Seizures and or loss of consciousness